Vitamin B2

Description
Whole-blood vitamin B2 (flavin adenine dinucleotide (FAD)) is measured by HPLC with fluorescence detection Due to the relocation of the Nutristasis service to the Blackfriars Hub site, this test is not currently accredited by UKAS to ISO15189
Clinical details
The term ‘vitamin B2' indicates three compounds with vitamin B2 activity found in nature; flavin adenine dinucleotide (FAD), flavin mononucleotide (FMN) and riboflavin. Vitamin B2 can be found in most unprocessed foods and at high concentrations in yeast extract liver and kidney. Meat, milk eggs and wheat bran are important dietary sources of vitamin B2 in the general population. Because of its wide distribution in foods, symptoms of vitamin B2 deficiency are hard to distinguish in malnourished individuals due to concomitant deficiencies in other micronutrients. Experimentally, signs of deficiency are lesions of the lips (cheilosis), angles of the mouth (angular stomatitis), a fissured and magenta coloured tongue (glossitis) and follicular keratosis of the nose and forehead. The eyes can also be effected, symptoms include corneal vascularisation and photophobia.
Related condition
Reference range

174-471

Units
nmol/L
Synonyms
Riboflavin; flavin adenine dinucleotide (FAD), flavin mononucleotide (FMN)
Testing site
Synnovis : Reference Services : Blackfriars Hub
Laboratory
Nutristasis Unit
Sample type and volume required
Minimum sample volume = 500 μL of EDTA whole blood
Call in advance
No
Special sample instructions

Protect specimens from light and store frozen at -20 degrees.

Storage and transport
Transport at room temperature
Turnaround time
10 days
Patient description
Whole-blood vitamin B2 (flavin adenine dinucleotide (FAD)) is measured by HPLC with fluorsence detection
Contacts

Nutristasis Unit at Blackfriars Hub
Phone: 0204 591 0055
Email: Nutristasis@synnovis.co.uk
Nutristasis
Floor 1, Synnovis Hub
Friars Bridge Court
41-43 Blackfriars Road
London
SE1 8NZ

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