Varicella-zoster IgG
- Description
- Qualitative chemiluminescent immunoassay (CLIA) for IgG antibodies to Varicella zoster virus in serum, used to determine immune status. This test is NOT suitable for diagnosis of chickenpox or shingles. Instead, a swab should be sent for molecular testing. If an urgent VZV IgG test is required following contact with chickenpox or shingles, contact on-call Infection StR via the hospital switchboard. This assay is available routinely Mon to Fri. This test is not UKAS accredited
- Clinical details
- Varicella-zoster virus is the causative agent of Chickenpox. Initial symptoms may include nausea, fever, aching, painful muscles, headache, generally feeling unwell, and loss of appetite. These are followed by a characteristic itchy red vesicular rash, covering the whole body. Complications such as pneumonia, septicaemia (blood poisoning), and meningitis may occur in neonates less than four weeks old, pregnant females and those of any age with a suppressed immune system. Infection during pregnancy may lead to fetal infection. Although rare this can cause serious complications including, scarring of the skin, eye defects, shortened limbs, and brain damage. After a chickenpox infection, the virus stays dormant in the body's nerve tissues and may reactivate, causing shingles.
- Related condition
- Reference range
Not Applicable
- Units
- Milli-international units per milliliter (mIU/mL): numerical values < 250 mIU/mL are stated, numerical values >250 mIU/mL are reported as "Detected"
- Synonyms
- VZV
- Testing site
- Synnovis : Infection Sciences : Blackfriars Hub
- Laboratory
- Virology
- Sample type and volume required
- 2.5 - 5ml Yellow Top Serum Separation Tube (SST) Clotted Blood (for serum).
- Storage and transport
- Place labelled sample in a sealed sample bag and send to Central Specimen Reception (CSR). To prevent sample haemolysis please store samples in refrigerator if a delay in sending samples to CSR is unavoidable.
- Turnaround time
- 4 working days
- Contacts
Infection Sciences Department at St Thomas’ Hospital
Phone: 020 7188 8008
St Thomas’ Hospital
North Wing – 5th Floor
Westminster Bridge Road
London SE1 7EHSouth London Specialist Virology Centre
Phone – Results: 02032996155
Phone – Medical Advice: 02032996298
King’s College Hospital
Cheyne Wing, 2nd Floor (opposite Liver ITU)
Denmark Hill
London SE5 9RS
DX address: South London (PHL) Kings DX 6570200 Peckham 90SE