Treponema pallidum Serology

Description
Serology tests for diagnosis, confirmation and monitoring of Treponema pallidum infection. A CMIA (chemiluminescent microparticle immunoassay) is the screening test. Confirmatory tests are made with an additional qualitiative EIA and/or a specific particle agglutination test (TPHA). All new and past CMIA positives are tested for Rapid Plasma Reagin (RPR). Tests are not UKAS accredited
Clinical details
All suspected cases should be discussed with a sexual health specialist.
Related condition
Synonyms
Chancre, RPR, VDRL, TPPA, TPHA, Spirochete, Treponemal
Testing site
Synnovis : Infection Sciences : Blackfriars Hub
Laboratory
Virology
Sample type and volume required
2.5 - 5ml Yellow Top Serum Separation Tube (SST) Clotted Blood (for serum) or Cerebrospinal Fluid (CSF) in a sterile universal container with no additives.
Storage and transport
Place labelled sample in a sealed sample bag and send to Central Specimen Reception (CSR). To prevent sample haemolysis please store samples in refrigerator if a delay in sending samples to CSR is unavoidable.
Turnaround time
3 working days
Contacts

Infection Sciences Department at St Thomas’ Hospital
Phone: 020 7188 8008
St Thomas’ Hospital
North Wing – 5th Floor
Westminster Bridge Road
London SE1 7EH

South London Specialist Virology Centre
Phone – Results: 02032996155
Phone – Medical Advice: 02032996298
King’s College Hospital
Cheyne Wing, 2nd Floor (opposite Liver ITU)
Denmark Hill
London SE5 9RS
DX address: South London (PHL) Kings DX 6570200 Peckham 90SE

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