Treponema pallidum Serology

Description
Serology tests for diagnosis, confirmation and monitoring of Treponema pallidum infection. A CMIA (chemiluminescent microparticle immunoassay) is the screening test. Confirmatory tests are made with an additional qualitiative EIA and/or a specific particle agglutination test (TPHA). All new and past CMIA positives are tested for Rapid Plasma Reagin (RPR). Tests are not UKAS accredited
Clinical details
All suspected cases should be discussed with a sexual health specialist.
Related condition
Synonyms
Chancre, RPR, VDRL, TPPA, TPHA, Spirochete, Treponemal
Testing site
Synnovis : Infection Sciences : Blackfriars Hub
Laboratory
Virology
Sample type and volume required
2.5 - 5ml Yellow Top Serum Separation Tube (SST) Clotted Blood (for serum) or Cerebrospinal Fluid (CSF) in a sterile universal container with no additives.
Storage and transport
Place labelled sample in a sealed sample bag and send to Central Specimen Reception (CSR). To prevent sample haemolysis please store samples in refrigerator if a delay in sending samples to CSR is unavoidable.
Turnaround time
3 working days
Contacts
For the most up-to-date contact list and service information, please refer to the User Manual.

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