Parvovirus IgM

Description
Qualitative chemiluminescent immuno-assay for Parvovirus IgM antibodies. Test used for the diagnosis of primary parvovirus infection. Tested together with parvovirus IgG. Reliable following onset of rash in immunocompetent individuals. DNA testing may be required in immunocompromised hosts, sickle cell disease and pregnancy. This assay is available routinely Mon to Fri. This test is not UKAS accredited
Clinical details
Prodrome Fever Slapped cheek disease in children Fine, erythematous maculopapular rash arthralgia.arthropathy Depressed reticulocyte count and fall in Hb - Sickle cell/haemoglobinopathy patients may present with aplastic crisis during prodrome, before rash/arthropathy and serological response develop. - Immunocompromised patients may present with anaemia (or pancytopenia) during prodrome, without development of rash/arthropathy or detectable antibody response. - Parvo IgM may clear after one month, therefore parvo IgG alone may be detected following primary infection in pregnancy. Needs careful assessment
Related condition
Reference range

Not applicable

Units
Qualitative - Detected/Not Detected
Synonyms
Slapped cheek syndrome Fifth disease Erythema infectiosum Pregnancy Haemoglobinopathy Sickle cell disease Hydrops fetalis intrauterine transfusion FSGS
Testing site
Synnovis : Infection Sciences : Blackfriars Hub
Laboratory
Virology
Sample type and volume required
2.5 - 5ml Yellow Top Serum Separation Tube (SST) Clotted Blood (for serum).
Storage and transport
Place labelled sample in a sealed sample bag and send to Central Specimen Reception (CSR). To prevent sample haemolysis please store samples in refrigerator if a delay in sending samples to CSR is unavoidable.
Turnaround time
8 days
Contacts
For the most up-to-date contact list and service information, please refer to the User Manual.

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