Parvovirus IgM

Description
Qualitative chemiluminescent immuno-assay for Parvovirus IgM antibodies. Test used for the diagnosis of primary parvovirus infection. Tested together with parvovirus IgG. Reliable following onset of rash in immunocompetent individuals. DNA testing may be required in immunocompromised hosts, sickle cell disease and pregnancy. This assay is available routinely Mon to Fri. This test is not UKAS accredited
Clinical details
Prodrome Fever Slapped cheek disease in children Fine, erythematous maculopapular rash arthralgia.arthropathy Depressed reticulocyte count and fall in Hb - Sickle cell/haemoglobinopathy patients may present with aplastic crisis during prodrome, before rash/arthropathy and serological response develop. - Immunocompromised patients may present with anaemia (or pancytopenia) during prodrome, without development of rash/arthropathy or detectable antibody response. - Parvo IgM may clear after one month, therefore parvo IgG alone may be detected following primary infection in pregnancy. Needs careful assessment
Related condition
Reference range

Not applicable

Units
Qualitative - Detected/Not Detected
Synonyms
Slapped cheek syndrome Fifth disease Erythema infectiosum Pregnancy Haemoglobinopathy Sickle cell disease Hydrops fetalis intrauterine transfusion FSGS
Testing site
Synnovis : Infection Sciences : Blackfriars Hub
Laboratory
Virology
Sample type and volume required
2.5 - 5ml Yellow Top Serum Separation Tube (SST) Clotted Blood (for serum).
Storage and transport
Place labelled sample in a sealed sample bag and send to Central Specimen Reception (CSR). To prevent sample haemolysis please store samples in refrigerator if a delay in sending samples to CSR is unavoidable.
Turnaround time
8 days
Contacts

Infection Sciences Department at St Thomas’ Hospital
Phone: 020 7188 8008
St Thomas’ Hospital
North Wing – 5th Floor
Westminster Bridge Road
London SE1 7EH

South London Specialist Virology Centre
Phone – Results: 02032996155
Phone – Medical Advice: 02032996298
King’s College Hospital
Cheyne Wing, 2nd Floor (opposite Liver ITU)
Denmark Hill
London SE5 9RS
DX address: South London (PHL) Kings DX 6570200 Peckham 90SE

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