Herpes Simplex Virus (HSV) Serology

Description
Qualitative chemiluminescent assay for type specific antibodies to HSV-1 and -2. The initial test detects both HSV-1 and -2 IgG. Positive samples are then tested for type-specific HSV-2 IgG. HSV seroconversion may not be detected until several months following a primary infection. Do not request for acute diagnosis; instead send appropriate sample for PCR. This test is available routinely Mon to Fri. This test is not UKAS accredited
Clinical details
Gingivostomatitis in primary orolabial herpes infection Orolabial herpes encephalitis. Keratitis/dendritic ulcer meningitis Mollaret's syndrome retinitis disseminated herpes fulminant herpes hepatitis neonatal herpes genital herpes Encephalitis . immunocompromised host
Related condition
Reference range

Not applicable

Units
Qualitative - Detected/Not detected
Synonyms
HSV, herpes
Testing site
Synnovis : Infection Sciences : Blackfriars Hub
Laboratory
Virology
Sample type and volume required
2.5 - 5ml Yellow Top Serum Separation Tube (SST) Clotted Blood (for serum).
Special sample instructions

Consult Virology Registrar if encephalitis suspected.

Storage and transport
Place labelled sample in a sealed sample bag and send to Central Specimen Reception (CSR). To prevent sample haemolysis please store samples in refrigerator if a delay in sending samples to CSR is unavoidable.
Turnaround time
3 working days
Contacts

Infection Sciences Department at St Thomas’ Hospital
Phone: 020 7188 8008
St Thomas’ Hospital
North Wing – 5th Floor
Westminster Bridge Road
London SE1 7EH

South London Specialist Virology Centre
Phone – Results: 02032996155
Phone – Medical Advice: 02032996298
King’s College Hospital
Cheyne Wing, 2nd Floor (opposite Liver ITU)
Denmark Hill
London SE5 9RS
DX address: South London (PHL) Kings DX 6570200 Peckham 90SE

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