Hepatitis B surface Ab

Description
Quantitative chemiluminescent immunoassay (CLIA) for the quantification of Hepatitis B surface antibodies in serum. Used to determine vaccine response and natural immunity. This assay is available as a screening or follow-up test Mon to Sun. This test is not UKAS accredited
Clinical details
Used to determine vaccine response or natural immunity to Hepatitis B.
Related condition
Reference range

Post primary vaccination course in immunocompetent individuals: >100 mIU/ml, further testing not needed, re-inforcing vaccine at 5yrs. >10 - <100mIU/ml, 1 further primary vaccine and re-inforcing vaccine at 5yrs, further testing not needed. <10mIU/ml, non-response to vaccine course, check for markers of current infection. Repeat vaccination course and testing 4 months post 2nd complete course. Individuals with levels of <10 mIU/ml post-vaccination requires Hepatitis B immunoglobulin if exposed to Hepatitis B.

Units
milli-International Units/ml (mIU/ml)
Testing site
Synnovis : Infection Sciences : Blackfriars Hub
Laboratory
Virology
Sample type and volume required
2.5 - 5ml Yellow Top Serum Separation Tube (SST) Clotted Blood (for serum). Note: If using Electronic Patient Record (EPR) please order "Hepatitis B surface Ab-mIU/ml".
Storage and transport
Place labelled sample in a sealed sample bag and send to Central Specimen Reception (CSR). To prevent sample haemolysis please store samples in refrigerator if a delay in sending samples to CSR is unavoidable.
Turnaround time
3 working days
Contacts

Infection Sciences Department at St Thomas’ Hospital
Phone: 020 7188 8008
St Thomas’ Hospital
North Wing – 5th Floor
Westminster Bridge Road
London SE1 7EH

South London Specialist Virology Centre
Phone – Results: 02032996155
Phone – Medical Advice: 02032996298
King’s College Hospital
Cheyne Wing, 2nd Floor (opposite Liver ITU)
Denmark Hill
London SE5 9RS
DX address: South London (PHL) Kings DX 6570200 Peckham 90SE

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