Hepatitis B core total antibodies

Description
Qualitative chemiluminescent immunoassay (CLIA) for the detection of total antibodies to Hepatitis B core in serum. A positive core antibody indicates past or current infection with Hepatitis B. Positive samples will undergo further testing for other Hepatitis B markers to determine whether there is chronic ongoing infection. Patients with a positive core antibody in isolation are still at risk of re-activating hepatitis B if significantly immunosuppressed. May be temporarily positive in patients who have recently received blood products, "false positive". This assay is available as a screening or follow-up test Mon to Sun, with a turnaround time of 3 working days. This test is not UKAS accredited
Clinical details
Hepatitis B infection can lead to significant liver disease which can be prevented either by pre-exposure vaccination or with medical treatment in chronic infection.
Related condition
Reference range

Not Applicable

Units
Qualitative test - Detected/Not detected
Synonyms
HepB, HBV, Core total
Testing site
Synnovis : Infection Sciences : Blackfriars Hub
Laboratory
Virology
Sample type and volume required
2.5 - 5ml Yellow Top Serum Separation Tube (SST) Clotted Blood (for serum).
Storage and transport
Place labelled sample in a sealed sample bag and send to Central Specimen Reception (CSR). To prevent sample haemolysis, please store samples in refrigerator if there is a delay in sending samples to CSR.
Turnaround time
3 working days
Contacts
For the most up-to-date contact list and service information, please refer to the User Manual.

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