Desmoglein-1 (DSG1) and desmoglein-3 (DSG3) antibody detection by ELISA

Description
Quantitation of anti-DSG1 and anti-DSG3 IgG antibodies is performed on serum samples using automated ELISA methodologies. This is a quantitative test for detection of both antibodies which are strongly associated with diseases of the pemphigus family. The test provides diagnostic confirmation, disease sub-typing and treatment monitoring information in these patients and results are typically combined with indirect immunofluorescence data for initial diagnostic purposes.
Related condition
Reference range

<30

Units

U/ml (arbitrary)

Synonyms

Skin antibodies, DSG, ELISA

Testing site
Synnovis : Tissue Sciences : St Thomas' Hospital
Laboratory
Immunodermatology
Sample type and volume required

1x serum separator tube (SST) or at least 0.5 ml pre-separated serum

Special sample instructions

SST should be received in lab within 48 hours of collection (1 month for separated serum stored at 4°C).

Turnaround time

8 working days

Contacts

Immunodermatology Laboratory at St Thomas’
Phone: 020 7188 6364
Email: immunodermatology@synnovis.co.uk
St John’s Institute of Dermatology
St Thomas’ Hospital
Westminster Bridge Road
London SE1 7EH
Opening hours: Mon-Fri, 09:00 -17:00

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