Tramadol and metabolites
- Description
- Tramadol, N-desmethyltramadol and O-desmethyltramadol by LC-HR-MS
- Clinical details
- Tramadol is an opioid analgesic with significant abuse potential. It is metabolised to O- and N-desmethyltramadol, both of which are measured separately and are reported together with the parent drug to give a 'otal tramadol' concentration in urine samples.
- Reference range
(cut-off) 200 µg/L
- Testing site
- Synnovis : Reference Services : King's College Hospital
- Laboratory
- Drugs of Abuse
- Sample type and volume required
- Random urine sample (10-20 mL) collected into a plain 30 mL universal container. Please ensure containers are tightly sealed, and are sent in a clear plastic bag separate from the accompanying request form. Please also ensure containers are labelled with the full name and date of birth of the client, and the specimen collection date and time.
- Special sample instructions
Additional specialist tests by enzymatic assay (urine ethanol), immunoassay (barbiturates), and by LC-HR-MS (buprenorphine and metabolites, ketamine and norketamine, and mephedrone - see other analytes in the ‘Our Tests’ section of the website) are available on request, and can be carried out on the same specimen as supplied originally.
- Storage and transport
- Please refrigerate (if possible) if not sending immediately. Send by first class post.
- Turnaround time
- 3-5 working days