Rubella IgG

Description
Quantitative chemiluminescent immuno-assay for Rubella IgG antibodies (Architect, Abbott Diagnostics). Assay is used for rubella immunity screening and investigation of individuals presenting with a rash or contact with a rubella like-illness particularly if pregnant (a rubella IgM assay is also required for clinical non screening cases). This test is not UKAS accredited
Clinical details
Rubella is usually a mild infection. However, if acquired in pregnancy it can give rise to congenital abnormalities such as heart defects, cataracts and deafness. Rubella can produce a maculopapular rash and arthralgia/arthritis and thrombocytopenia may also occur. Rubella is clinically indistinguishable from parvovirus B19 and pregnant women with a rash or contact with a rubella-like illness should be investigated for both infections. The UK immunisation programme has resulted in rubella and congenital rubella now being rare in the United Kingdom. Screening is recommended for pregnant women.
Related condition
Reference range

Values <10 IU/ml are resulted as 'Rubella antibodies not detected' with a recommendation for vaccination with Measles/Mumps/Rubella vaccine. Values >10 IU/ml are resulted as 'Rubella antibodies detected'

Units
Not applicable
Synonyms
German measles, rubella-like illness, rash
Testing site
Synnovis : Infection Sciences : Blackfriars Hub
Laboratory
Virology
Sample type and volume required
2.5 - 5ml Yellow Top Serum Separation Tube (SST) Clotted Blood (for serum).
Storage and transport
Place labelled sample in a sealed sample bag and send to Central Specimen Reception (CSR). To prevent sample haemolysis please store samples in refrigerator if a delay in sending samples to CSR is unavoidable.
Turnaround time
3 working days
Contacts
For the most up-to-date contact list and service information, please refer to the User Manual.

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