This antibody is one of a group of antibodies commonly referred to as “functional antibodiesâ€. The others in this designation are anti-Haemophilus influenzae type b, anti-Tetanus toxin antibodies. There are 3 anti-pneumococcal antibody assays measuring IgG, IgG2 subclass and serotype specific IgG pneumococcal antibodies.
Functional antibodies are useful tests in the investigation of antibody deficiency especially in those with IgG subclass deficiency and individuals with a history of recurrent infections but normal serum immunoglobulins.
Normal or reference ranges are not internationally agreed. Pneumococcal antibody levels can be difficult to interpret in children. Please contact Immunology if you need help with interpretation of the results.
Reference range
None, to be interpreted in the light of the clinical details.
Units
mg/L
Testing site
Synnovis : Reference Services : Blackfriars Hub
Laboratory
Diagnostic Immunology
Sample type and volume required
Clotted (Gold top vacutainer)
Special sample instructions
All tests are compromised by prolonged transit times. For this reason, date of bleed and date of postage must be provided with each request.
Immunisation history with dates must be given with all requests for specific antibodies.
Storage and transport
Serum stored at 4°C should be sent by first class post
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