PD-L1 Testing
- Description
- PD-L1 is an immune-related biomarker that is expressed on tumour cells in various tumour types, including Non Small Cell Lung Cancer (NSCLC). Assessing PD-L1 expression in squamous and non-squamous NSCLC may contribute to a better understanding of a patient's tumour and KEYTRUDA is indicated for the treatment of patients with metastatic NSCLC whose tumours express PD-L1. PD-L1 expression helps identify patients that are most likely to benefit from KEYTRUDA
- Clinical details
- The Dako PD-L1 22C3 pharmDx™ kit is a qualitative assay intended for use in the detection of PD-L1 in formalin-fixed, paraffin-embedded (FFPE) in non−small-cell lung carcinoma (NSCLC) using the Dako Autostainer Link 48 platform
- Related condition
- Synonyms
- Programmed Death Ligand 1
- Testing site
- Synnovis : Tissue Sciences : St Thomas' Hospital
- Laboratory
- Histology/ Histopathology
- Sample type and volume required
- Sample Type: Formalin-fixed, paraffin-embedded (FFPE) slides Volume: Fresh H&E slide and 3 unstained slides
- Special sample instructions
- Collection: unstained slides on positive-charged slides sectioned at 3 microns, sectioned of no more than one month age
- Storage and transport
- Refrigerate and protect from light and submit within 4 weeks of sectioning
- Turnaround time
- 5 working days
- Contacts
Histopathology Laboratory at Blackfriars Hub
Phone: 020 4614 7519/ 7522
Friars Bridge Court,
41-43 Blackfriars Road,
London, SE1 8NZHistology Laboratory at Princess Royal University Hospital
Phone: 01689 864314
Princess Royal University Hospital
Farnborough Common
Orpington
Kent
BR6 8NDCellular Pathology/Histopathology at King’s College Hospital
Phone: 020 3299 3045
kch-tr.histopathologyoffice@nhs.net
King’s College Hospital
Bessemer Wing – 2nd Floor
Denmark Hill
London SE5 9RSCellular Pathology at St Thomas’ Hospital
Phone – Histology: 0207 188 7188 extension 54611
Phone – Cytology: 0207 188 2915
Phone – Oral Pathology: 0207 188 4367
Histopathology & Cytopathology Laboratories
Cellular Pathology
St Thomas’ Hospital
North Wing – 2nd Floor
Westminster Bridge Road
London SE1 7EHCellular Pathology at Guy’s Hospital
Head and Neck/Oral Pathology Laboratory
4th Floor, Tower Wing
Guy’s Hospital
Great Maze Pond
London SE1 9RT