Interphase FISH Analysis for Translocations in Lymphomas
- Description
- Fluorescent in situ hybridisation analysis is recommended for the detection of translocations involving the BCL2, CCND1 (cyclin D1/BCL1), MYC, BCL6, ALK1 and MALT1 loci, detected in lymphomas. It has been demonstrated as invaluable for the diagnosis of lymphomas especially in small samples such as core biopsies and FNAs. This can be carried out in paraffin processed tissue and in conjunction with conventional immunohistochemical staining for these three proteins.
- Testing site
- Synnovis : Tissue Sciences : St Thomas' Hospital
- Laboratory
- Histology/ Histopathology
- Sample type and volume required
- Formalin fixed paraffin processed tissue which *ideally* has not been decalcified in acid.
- Storage and transport
- First class post within 4 days (temperature not to exceed 30°C during transport)
- Turnaround time
- 1 - 2 weeks
- Contacts
Histopathology Laboratory at Blackfriars Hub
Phone: 020 4614 7519/ 7522
Friars Bridge Court,
41-43 Blackfriars Road,
London, SE1 8NZHistology Laboratory at Princess Royal University Hospital
Phone: 01689 864314
Princess Royal University Hospital
Farnborough Common
Orpington
Kent
BR6 8NDCellular Pathology/Histopathology at King’s College Hospital
Phone: 020 3299 3045
kch-tr.histopathologyoffice@nhs.net
King’s College Hospital
Bessemer Wing – 2nd Floor
Denmark Hill
London SE5 9RSCellular Pathology at St Thomas’ Hospital
Phone – Histology: 0207 188 7188 extension 54611
Phone – Cytology: 0207 188 2915
Phone – Oral Pathology: 0207 188 4367
Histopathology & Cytopathology Laboratories
Cellular Pathology
St Thomas’ Hospital
North Wing – 2nd Floor
Westminster Bridge Road
London SE1 7EHCellular Pathology at Guy’s Hospital
Head and Neck/Oral Pathology Laboratory
4th Floor, Tower Wing
Guy’s Hospital
Great Maze Pond
London SE1 9RT