Glucose 6 Phosphate Dehydrogenase Assay
- Description
- G6PD deficiency is a common hereditary enzyme deficiency causing varying degrees of haemolytic anemia; can cause favism, some drug induced haemolytic anemias, and chronic nonspherocytic haemolytic anemia. Any samples with a deficient screen or reticulocyte levels >150 x 10 9/L will have a G6PD assay performed.
- Reference range
Glock & McLean method: 5.2 – 11.5 IU/g Hb
Pointe Scientific method: 6.6 – 13.8 IU/g Hb
- Testing site
- Synnovis : Blood Sciences : Blackfriars Hub
- Laboratory
- Red Cell Centre - Protein
- Sample type and volume required
Minimum 1 ml EDTA blood. If more than one enzyme assay is required then > 1.0 ml of blood will be required. Full blood count and reticulocyte must be performed and results sent with samples.
- Special sample instructions
Blood transfusion within the last four months will affect results. Any red cell transfusion given must be declared on the request form.
Raised reticulocyte levels and/or raised WBC levels may affect assay.
- Storage and transport
Samples can be sent first class post. Samples must be received in the laboratory within 3 days of collection. If there is a delay in sending store at 4°C and send a normal sample collected on the same day to act as a travel control.
- Turnaround time
10 working days
- Cost
Please contact Business Development for pricing enquiries
- Time limit for extra tests
Depends on tests required. Contact laboratory for further details.
- Contacts
Special Haematology Department St Thomas’ Hospital
Phone – 020 7188 8189
St Thomas’ Hospital
5th Floor – North Wing
Westminster Bridge Road
London SE1 7EHSpecial Haematology Department at Guy’s Hospital
Phone – 020 7188 3421
Guy’s Hospital
4th Floor – Southwark Wing
Great Maze Pond
London SE1 9RTRed Cell Centre – Protein Laboratory
Phone: 020 3299 2455
Email: kch-tr.redcelllab@nhs.net
Central Specimen Reception
Blood Sciences Laboratory
Ground Floor Bessemer Wing
King’s College Hospital
Denmark Hill
London SE5 9RS