Fractional excretion of uric acid: FJHN / gout / hereditary renal hypouricaemia

Description
The fractional excretion of uric acid collection is decreased in gout and familial juvenile hyperuricaemia, also known as autosomal dominant tubulointerstitial kidney disease (ADTKD).
Clinical details
The fractional excretion of uric acid (FEur) is decreased in under-excreting gout and autosomal dominant tubulointerstitial kidney disease. FEur may be dramatically increased in patients with hereditary renal hypouricaemia.
Related condition
Reference range

Please contact the laboratory to discuss

Units
24h urine collection
Testing site
Synnovis : Reference Services : St Thomas' Hospital
Laboratory
Purine Research
Sample type and volume required
EDTA (purple top) and Lithium heparin (green top), 24 h urine collected with thymol
Storage and transport
10ml aliquot of warmed ( sink of hot water, 30min), well mixed 24h urine, store in fridge or freezer, can thaw in 1st class post.
Turnaround time
3 weeks

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