ENA (Extractable Nuclear Antigens)
- Description
- The identification of autoantibodies to the ENA family is an integral component in the investigation of the rheumatological disorders. Antibodies to SS-A (Ro) and SS-B (La) are mainly associated with Sjogren's syndrome but may be found in SLE and less frequently in other autoimmune disorders. Anti-Sm and anti-RNP are associated with SLE and mixed connective tissue disease. Anti-Scl 70 is associated with scleroderma while anti-Jo-1 is seen in dermatomyositis.
- Reference range
- Negative
- Units
- Negative - Positive
- Synonyms
- Sjogren's syndrome
- Testing site
- Synnovis : Reference Services : Blackfriars Hub
- Laboratory
- Diagnostic Immunology
- Sample type and volume required
- Clotted (Gold top vacutainer)
- Special sample instructions
All tests are compromised by prolonged transit times. For this reason, date of bleed and date of postage must be provided with each request.
- Turnaround time
- 4 working days
- Time limit for extra tests
- 10 days