Mycophenolic acid
- Description
- Therapeutic drug monitoring for patients on immunosuppressant drugs. Analysis by tandem mass spectrometry. Please send a request form with adequate patient information and clear contact details to enable efficient communication of results.
- Clinical details
- Mycophenolic acid (MPA) is an immunosuppressive agent which exerts it's effect by inhibiting the growth of B and T cells of the immune system. It is important to monitor the blood concentration of MPA as at toxic concentrations patients are susceptible to a number of side effects including leukopenia and anaemia. At sub-therapeutic dosage patients may experience transplant rejection. MPA is increasingly used as a steroid-sparing treatment in other autoimmune mediated disorders, for example psoriasis.
- Related condition
- Reference range
Suggested therapeutic range: 1 – 3.5mg/L
- Units
- mg/L
- Synonyms
- Immunosuppressant, MPA, Mycophenolate, Mycophenolic acid
- Testing site
- Synnovis : Reference Services : King's College Hospital
- Sample type and volume required
- EDTA Plasma - 100ul minimum
- Storage and transport
- Same day: send ambient by courier Within 2 days: store refrigerated and then send ambient by courier More than 2 days: send frozen (dry ice not required)
- Turnaround time
- 24 hours of sample receipt.
- Contacts
Immunosuppressive Drug Monitoring (IDM) Service at King’s
Phone: 020 3299 3147
Email: IDM@synnovis.co.uk
Institute of Liver Studies
Cheyne Wing – 3rd Floor
King’s College Hospital
Denmark Hill
London
SE5 9RSImmunosuppressant Monitoring Service at Harefield Hospital
Phone: 01895 828570
Email: ims-lab.harefield@nhs.net
Harefield Hospital
Pathology block
Hill End Road
Harefield
UB9 6JH