HLA Typing (Class I and Class II) for Solid Organ and Stem Cell Transplantation

Description
A variety of methods and technologies are used, including Next Generation Sequencing (NGS), PCR-SSP and PCR-SSOP (Luminex) to determine HLA Class I (HLA-A, B, C) and HLA Class II (DRB1/3/4/5, DQB, DQA, DPB, DPA) alleles. The results achieved can be reported at a variety of resolution from low (1st field) to high (3rd Field) as required. Routinely all initial HLA types will be tested by NGS to high resolution, 2nd Field, unless otherwise requested.
Clinical details
HLA typing for work up for solid organ transplant or stem cell transplantation - recipient or donor - to allow for assessment of HLA compatibility.
Related condition
Reference range

none

Units
none
Synonyms
HLA typing, transplant
Testing site
Synnovis : Reference Services : Guy's Hospital
Laboratory
Clinical Transplantation Laboratory
Sample type and volume required
10ml EDTA blood
Call in advance
No
Special sample instructions

none

Storage and transport
UN3373 packaging, room temperature
Turnaround time
10 working days
Time limit for extra tests
none
Contacts

Clinical Transplantation Laboratory at Guy’s Hospital
Phone: 020 7188 1540
Clinical Transplantation Laboratory
Guy’s Hospital
Borough Wing – 3rd Floor
Great Maze Pond
London SE1 9RT

Email: gstt.ctl@nhs.net

Last updated:

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