Urinary Ethyl glucuronide(ETG) and Urinary ethyl sulphate (ETS) by LCMS
- Description
- Urinary Ethyl glucoronide (EtG) and urinary ethyl sulphate (ETS) measured by liquid chromatography tandem mass spectrometry (LC-MS/MS)
- Clinical details
Ethyl glucuronide (EtG) and ethyl sulfate (EtS) are metabolites of ethanol and are measured to assess recent alcohol consumption. Research data suggests that EtG is detectable in urine for 72-90 hours (Wienmann et al., 2004). There have been far fewer studies carried out on EtS but work done by Hoiseth et al (2008) suggested that EtS is detectable in urine for at least 40 hours. Therefore, quantitation of urinary EtG and EtS can provide an objective measure of alcohol abstinence and can be used in the evaluation of liver transplant patients.
- Related condition
- Reference range
EtG: <200 μg/L, EtS: <100 μg/L
- Units
μg/L
- Testing site
- Synnovis : Reference Services : Blackfriars Hub
- Laboratory
- Metabolic
- Sample type and volume required
Urine
- Storage and transport
Due to the possibility of false positive and false negative EtG results it is advisable to transport and store samples at -20 ºC until analysis.
- Turnaround time
10 days
- Contacts
Metabolic Laboratory at Blackfriars Hub
Phone: 020 4591 0011
Email: Metabolic.Laboratory@synnovis.co.uk
Metabolic Laboratory at Synnovis
Reference Chemistry, Floor One
Friars Bridge Court, 41-43 Blackfriars Road
London, SE1 8NZ