Fibrinogen Beta -148 C>T Polymorphism
- Description
- Direct detection of the FGB -148C>T promoter polymorphism.
- Clinical details
- This polymorphism is associated with elevated plasma fibrinogen levels, with individuals with the TT genotype having significantly higher levels than CC individuals. There is an established association between raised fibrinogen levels and the risk for myocardial infaction (MI) and coronary artery disease (CAD). However, the association between FGB -148 and MI or CAD is less clear.
- Related condition
- Reference range
n/a
- Units
- n/a
- Synonyms
- Fibrinogen promoter polymorphisms.
- Testing site
- Synnovis : Genomics : St Thomas' Hospital
- Laboratory
- Molecular Haemostasis
- Sample type and volume required
- 1 x Edta
- Call in advance
- no
- Storage and transport
- transport at ambient temperature
- Turnaround time
- 14 days
- Contacts
Molecular Haemostasis Laboratory at St Thomas’ Hospital
Phone: 020 7188 2798
Haemostasis and Thrombosis
North Wing – 4th floor
St Thomas’ Hospital
Westminster Bridge Road
London SE1 7EH
Laboratory opening times
Monday – Friday 09.00 – 17.00