Centromere antibodies
- Description
- Anti-centromere antibody is associated with CREST syndrome. It is not however an exclusive association as this autoantibody has been detected in other rheumatological disorders including systemic lupus erythematosus (SLE). This investigation is currently performed by indirect immunofluorescence using a HEp-2 cell line.
- Related condition
- Reference range
- Negative
- Units
- Negative / positive
- Synonyms
- Scleroderma
- Testing site
- Synnovis : Reference Services : Blackfriars Hub
- Laboratory
- Diagnostic Immunology
- Sample type and volume required
- Clotted (Gold top vacutainer)
- Special sample instructions
All tests are compromised by prolonged transit times. For this reason, date of bleed and date of postage must be provided with each request.
- Storage and transport
- Serum stored at 4°C should be sent by first class post
- Turnaround time
- 4 working days
- Time limit for extra tests
- 10 days