C5 Isobars
- Description
- The C5 isobar test is a second line screening test which is indicated when an increased C5 carnitine result is obtained by Newborn Screening Programme Centre. Four different isobars (isovalerylcarnitine, pivaloylcarnitine, valerylcarnitine and 2-methylbutyrylcarnitine) can contribute to C5 increase. The aim of the test is to identify which compound is present in the sample to aid interpretation of the screening result.
- Reference range
Qualitative analysis only – results are reported as an interpretive comment.
- Testing site
- Synnovis : Reference Services : Blackfriars Hub
- Laboratory
- Inherited Metabolic Disease
- Sample type and volume required
Capillary blood spotted onto a Newborn Screening blood spot card (Guthrie card). Minimum one spot of 7 mm diameter.
- Call in advance
Yes
- Special sample instructions
Allow to dry at room temperature prior to packaging.
- Storage and transport
Send via first class post. Samples should be received within the laboratory within 14 days of collection.
- Turnaround time
Same day from SE Thames NBS lab, five working days for samples from external NBS laboratories.
- Contacts
Inherited Metabolic Diseases Unit at Blackfriars Hub
Phone: 020 4591 0070
IMD Duty Biochemist: 07592 502653
Email: ClinicalScientistIMD@synnovis.co.uk
Reference Chemistry
Floor 1, Synnovis hub
Friars Bridge Court
41-43 Blackfriars Road
London
SE1 8NZ