Free erythrocyte protoporphyrin (FEP)
- Description
- FEP is a test offered by the SAAS Porphyria Service in Reference Biochemistry at King's College Hospital. Quantitative measurement of FEP is reported with zinc protoporphyrin (ZPP) using fluorescence spectroscopy.
- Clinical details
- FEP is present in red blood cells and combines with iron to form haem. FEP is elevated in patients with erythropoietic protoporphyria (EPP) and X-linked protoporphyria (XLPP).
- Reference range
<200 nmol/L red cells
- Synonyms
- FEP
- Testing site
- Synnovis : Reference Services : King's College Hospital
- Laboratory
- Porphyrins and Gastrointestinal
- Sample type and volume required
- 5 - 10 ml whole blood collected into EDTA or heparin. Separate red cells and plasma if delay in dispatch. Specimens should be protected from light.
- Storage and transport
- Specimens can be sent by first class post without ice packs. Specimens are stable for several weeks if frozen while awaiting despatch.
- Turnaround time
- 1-2 weeks
- Contacts
Porphyrin Laboratory at Blackfriars Hub
Phone: 0208 078 8996
Email: PorphyrinLab@synnovis.co.uk
Porphyrin Laboratory
Floor 1, Synnovis hub
Friars Bridge Court
41-43 Blackfriars Road
London, SE1 8NZ